Research

About

Research is a fundamental part of what we do at Hamilton Health Sciences. In partnership with McMaster University, we have a decades-long track record of making discoveries that change how healthcare is delivered around the world.

Our culture of exploration and innovation has attracted top research talent from across Canada and beyond, and we’re consistently ranked among the country’s top research hospitals.

Learn more about research at Hamilton Health Sciences below.

Research Leadership Team

Dr. Salim Yusuf
Dr. Salim Yusuf
Chief Scientist

Dr. Salim Yusuf is the Founder and Executive Director of the Population Health Research Institute (PHRI), a joint member of the Department of Clinical Epidemiology & Biostatistics, a cardiologist at the Hamilton General Hospital, and a professor in the Department of Medicine at McMaster University.

Dr. Yusuf’s research interests include the prevention and treatment of cardiovascular disease and societal, biologic and, genetic determinants of population health in developing populations. His team's studies are conducted in 86 countries in all of the inhabited continents of the world.

Sandra Carroll headshot
Dr. Sandra Carroll
Director, Clinical Health Professional Research

Dr. Carroll is the Vice-Dean, Faculty of Health Sciences and Executive Director of the School of Nursing at McMaster University. She is also an Associate Scientist at the Population Health Research Institute of Hamilton Health Sciences and McMaster University. Dr. Carroll’s research interests include patients’ decision-making, decision support in the context of implantable defibrillators, patient preferences for cardiovascular treatments, and patient reported outcomes in arrhythmia care. Dr. Carroll has received operating funds from the Canadian Institutes of Health Research and the Heart & Stroke Foundation.

Dr. Ted Scott
Vice President, Research & Chief Innovation Officer

Dr. Scott brings resources, partnerships and thought leadership to healthcare innovation. He is Chair of the Synapse Life Sciences Consortium in Hamilton, and was previously Chief Innovation Officer and Dean of Applied Research at Mohawk College, where he studied Radiography and Sonography. Ted is an expert digital health strategist and has a wealth of experience in industry relations and procurement, as well as innovation policy. He returned to HHS where he started his career as a sonographer after working at The Hospital for Sick Children and Huntsville District Memorial Hospital. Ted is a lifelong learner who earned his Masters of Applied Science in Medical Ultrasound and his PhD in Diagnostic Imaging from Charles Sturt University of Australia.

Dr. Salim Yusuf is the Founder and Executive Director of the Population Health Research Institute (PHRI), a joint member of the Department of Clinical Epidemiology & Biostatistics, a cardiologist at the Hamilton General Hospital, and a professor in the Department of Medicine at McMaster University.

Dr. Yusuf’s research interests include the prevention and treatment of cardiovascular disease and societal, biologic and, genetic determinants of population health in developing populations. His team's studies are conducted in 86 countries in all of the inhabited continents of the world.

Dr. Carroll is the Vice-Dean, Faculty of Health Sciences and Executive Director of the School of Nursing at McMaster University. She is also an Associate Scientist at the Population Health Research Institute of Hamilton Health Sciences and McMaster University. Dr. Carroll’s research interests include patients’ decision-making, decision support in the context of implantable defibrillators, patient preferences for cardiovascular treatments, and patient reported outcomes in arrhythmia care. Dr. Carroll has received operating funds from the Canadian Institutes of Health Research and the Heart & Stroke Foundation.

Dr. Scott brings resources, partnerships and thought leadership to healthcare innovation. He is Chair of the Synapse Life Sciences Consortium in Hamilton, and was previously Chief Innovation Officer and Dean of Applied Research at Mohawk College, where he studied Radiography and Sonography. Ted is an expert digital health strategist and has a wealth of experience in industry relations and procurement, as well as innovation policy. He returned to HHS where he started his career as a sonographer after working at The Hospital for Sick Children and Huntsville District Memorial Hospital. Ted is a lifelong learner who earned his Masters of Applied Science in Medical Ultrasound and his PhD in Diagnostic Imaging from Charles Sturt University of Australia.

Reports & Publications

Our Institutes

Research at Hamilton Health Sciences happens across our many programs and services, and on varying scales. Much of our research is led by our five specialized research institutes. Together, they conduct research that advances patient care by bringing evidence into practice through translation and application in to real-world environments.

At Hamilton Health Sciences, our research happens in real-time at the bedsides of our patients and across our many programs and services. That research is supported by world-class infrastructure, including Canada’s largest biobank and a family of research institutes, each with expertise in a unique area which, collectively, cover the spectrum of health and disease. All of our research institutes are operated in partnership with McMaster University. Click on the images below to learn more.

Learn more about Hamilton Health Sciences’ research institutes below.

Population Health Research Institute

A world leader in large clinical trials and population studies, Population Health Research Institute (PHRI) is Canada’s premier cardiovascular research institute. World-class researchers conduct some of the largest studies in the world, spanning all frontiers of the globe and covering a broad spectrum of health-related issues. PHRI’s population science focus examines biological and genetic determinants, as well as social, environmental and policy factors, with an emphasis on risk factors and the prevention of heart attacks, stroke, diabetes, kidney disease and cognitive decline. PHRI has conducted more than 80 global trials and epidemiological studies in more than 1,500 centres, in 86 countries, in all inhabited continents.

Visit the PHRI website to learn more.

Escarpment Cancer Research Institute

The Escarpment Cancer Research Institute (ECRI) is focused on improving care for cancer patients by focusing on three thematic areas: clinical trials, quality health care and knowledge translation research, and transitional (bench-to-bedside) research. ECRI brings together successful, well-established teams with newly formed cancer research groups in order to embrace and create new opportunities for synergies in research.

Visit the ECRI website to learn more.

Thrombosis and Atherosclerosis Research Institute

The primary focus of the Thrombosis & Atherosclerosis Research Institute (TaARI) is research excellence in thrombosis and atherosclerosis. TaARI’s core research programs include the Experimental Thrombosis and Atherosclerosis Program, the Clinical Thromboembolism Program, the Biometrics Group, and the Comparative Medicine Program which focuses on the translation of basic research findings into clinically relevant models prior to evaluation in humans.

Visit the TaARI website to learn more.

Offord Centre for Child Studies

Research conducted at the Offord Centre has had an important impact in Ontario, in Canada, and internationally. It is commonly stated that one in five children in Canada have a mental health challenge. That statistic comes from the Offord Centre’s 1983 landmark study, The Ontario Child Health Study, one of the most important population-based studies on children’s mental health conducted anywhere in the last 30 years.

Visit the Offord Centre website to learn more.

GERAS Centre for Aging Research

The GERAS Centre is committed to educating and empowering seniors to regain and retain independence and to manage their health through active participation in their care. These new models of care engage family members and build capacity for support within the community. The experts at St. Peter’s Hospital are also dedicated to advancing healthcare education for the present and next generation of healthcare professionals. Through innovative research the GERAS Centre aims to close the gap between knowing and doing to contribute to improved quality of life for seniors.

Visit the GERAS Centre website to learn more.

Clinical Research Library and Biobank

The Clinical Research Laboratory and Biobank (CRLB) is a state-of-the-art research facility which provides comprehensive Central Laboratory services to support global clinical studies and innovative research. The facility has the capacity to accommodate 100 large storage tanks, each holding approximately 80,000 vials. Samples in the Biobank are linked to relevant clinical information relating to diabetes, obesity, cardiovascular disease, hypertension, stroke, kidney disease, fractures and cancer. It is the largest research biobank in Canada, with several million samples from around the world which support on-going research at Hamilton Health Sciences.

Visit the CRLB website to learn more.

Our Expertise

Hamilton Health Sciences’ Research Administration team is available to support the needs of the hospital’s research community by offering expertise in the following areas:

  • clinical contracts and agreements
  • clinical research ethics
  • development and relations
  • financial services
  • infrastructure support/resources
  • internal funding opportunities

Collaboration

We welcome opportunities to collaborate with fellow healthcare institutions and providers, research centres, and other industries on comprehensive research studies and trials that align to Hamilton Health Sciences’ research programs and vision.

Find more information about how to collaborate with us on research initiatives below.

Youth Outreach Programs

Hamilton Health Sciences has two highly sought-after Youth Outreach Programs designed to mentor the next generation.

Discovery Days In Health Sciences: A one-day symposium for Ontario high school students in grades 10-12 who are considering a career in Health Sciences.

High School Research Bursary: Designed for senior high school students interested in pursuing, or accepted into, university or college level post-secondary studies in Health or Life Sciences.

Capabilities

Hamilton Health Sciences has multiple clinical sites and a rich, collaborative research network. This has helped to accelerate the knowledge transfer process and ensure best proven practices for healthcare delivery.

Covering a broad spectrum of health research, HHS investigators explore basic laboratory, clinical and epidemiological research. Strict guidelines and policies combined with a sophisticated infrastructure support system ensure the highest level of data integrity, adherence to national and international regulations, and timely reports. Our teams provide start to completion expertise, including:

  • Conceptual development & protocol
  • Study design and set-up, data management, statistical analysis
  • Study initiation, site selection, recruitment, regulatory approval
  • Study maintenance: ongoing monitoring, study close-out, data analysis, central laboratory analysis, presentation of final results
  • Publication and dissemination of study results
  • Regulatory submissions, clinical trial reports

Contract Policies

Hamilton Health Sciences protects you and your patients with the following:

Legally-binding agreements

Confidentiality agreements, clinical trial agreements, site agreements, amendments, grant agreements, memorandum of understanding, data sharing agreements, material transfer agreements.

Internal Policies

The research contracts team ensures our internal policies on research, publication, intellectual property, insurance, etc. are followed.

CAHO – The Council of Academic Hospitals of Ontario

We base our clinical trial agreements on the CAHO Statement of Principles. In fact, we were on the CAHO Steering Committee that developed these principles.

CAHO Harmonization of Clinical Study Agreements Initiative

In an effort to reduce timelines and promote transparency in contract negotiation, HHS has adopted the document developed through an initiative of Council of Academic Hospitals of Ontario (CAHO) and entitled “Statement of Principles to be Considered when Negotiating a Clinical Studies Agreement” which can be accessed on the CAHO website, or is available for download here. HHS encourages companies to review and incorporate these principles into its clinical study agreement templates prior to entering into negotiations with us. If any of the items in the principles document are issues of concern, please do not hesitate to contact the Research Contracts Team to discuss them.

Contact Us

To learn more about collaborative opportunities with Hamilton Health Sciences Research, contact us:

293 Wellington St. N., Suite 120
Hamilton, ON

Innovation

The Research and Innovation Team welcomes opportunities to collaborate with fellow healthcare institutions and providers, research centres, and industry partners on various research and innovation projects that align to Hamilton Health Sciences’ research programs and vision. We are proud to have an environment that encourages and cultivates innovation through our initiatives and collaboration. Our team is equipped to offer additional services, support, and can help to identify different opportunities for our academic, public and private sector partners on an ad-hoc basis.

Hamilton Health Sciences also provides numerous resources to external research, public and private sector partners in order to assist their research translation and commercialization needs:

  • Identify and facilitate opportunities for collaboration with our rich and diverse research areas and investigators at HHS
  • Connections to HHS investigators to initiate basic research, pilot studies, feasibility, validation and clinical trials
  • Hands-on support with commercialization activities, grant applications, letters of support, contracts, agreements and research compliance.
  • Dedicated expertise to identify appropriate funding opportunities around R&D, knowledge translation, technology transfer, innovation, executive support, market access, etc.

Contact Us

To learn more about collaborative opportunities with Hamilton Health Sciences Research and Innovation, contact us:

researchinnovation@hhsc.ca
293 Wellington St N, Suite 132
Hamilton, Ontario

Internal Funding

**These funding opportunities are limited to Hamilton Health Sciences Researchers which includes McMaster University faculty members who must have a formal cross appointment with Hamilton Health Sciences**

Hamilton Health Sciences (HHS) takes a strategic approach in developing internal funding programs for its research community, including front-line staff. HHS invests approximately $1.6 million dollars annually to provide operating grants, career awards, and travel awards, as well as mentorship opportunities through two province-wide youth outreach programs. Funding and mentoring programs are awarded through peer-review competitions designed to support every career stage, from senior investigators with established, large-scale research studies, to early-career investigators initiating their first research study.

HHS Strategy Resource Documents:

HHS Corporate Strategic Plan
HHS Digital Health Plan
Planning Our Healthy Future

New Investigator Fund (NIF)

Hamilton Health Sciences’ commitment to “first stage” research led to the creation of the New Investigator Fund (NIF). The NIF provides a unique opportunity to foster and support a culture of inquiry for novice investigators under the mentorship of senior researchers. The NIF provides project funding to front-line staff ( who are healthcare professionals and medical staff) towards research initiatives directly relevant to the Clinical Mission, Strategy–Pillars and Strategic Directions of Hamilton Health Sciences. Priority areas for funding include the following:

  • Consistent with, and likely to enhance, the main clinical programs/priorities at HHS
  • Enhances research enterprise/profile at HHS
  • Multidisciplinary and collaborative (involving more than one department or program or healthcare discipline and institution)
  • Builds on existing research strengths
  • Advances and creates new knowledge that informs patient care by bringing evidence into practice through translation and application
  • Conduct of pilot or feasibility studies which could facilitate obtaining funding for full scale studies through independent peer review or other mechanisms.

​For more information contact Donna Catherwood, catherwood@hhsc.ca

Important Dates

Spring deadline: April 1
Fall deadline: October 1

Important Forms

NIF Application Form
NIF Budget Form
NIF Guidelines for Application
NIF Lay Summary Form 
NIF Progress & Completion Form

Submit to NIF@hhsc.ca

Early Research Career Awards (ECA)

“Dr. David Sackett’s legacy to carry forward for years to come through naming one of Hamilton Health Sciences Research Early Career Awards in his honour – recognizing his lifetime contribution and accomplishments in advancing medical sciences and in mentoring several generations of researchers.”

The Hamilton Health Sciences Research Early Career Awards (ECA) are research personnel stipends awarded annually. These Early Career Awards are to be used to help the applicant pursue research in their specialty area through either purchasing a portion of time for the applicant’s salary OR a portion of time for salaries of research personnel who are supervised by the applicant.

​For more information contact Donna Catherwood, catherwood@hhsc.ca

Important Dates

Submission deadline: November 15

Important Forms

ECA Application Form
ECA Guidelines for Application
ECA Renewal Report Form
ECA Year 3 Completion Report

Submit to: careerawards@hhsc.ca

Past Recipients 

2019 ECA Award Recipients

Health Professional Investigator Operating Grant (HPI)

Funding Available: up to $15,000 per grant: a total of three grants available for a one-year term.

The Health Professional Investigator (HPI) Operating Grant provides project funding to principal investigators (PI) who are HHS-employed healthcare professionals. Inter-professional teams, which include physicians, are encouraged, but physicians are not eligible to apply as lead PI for this grant. The HPI Operating Grant is for research initiatives directly relevant to the clinical mission and priorities/strategic plan of HHS (Patients, People, Sustainability, Innovation and Learning). The grant objective is to provide support for pilot studies or research projects that have the potential to lead to larger projects and the possibility of external funding. The HPI Operating Grant offers an opportunity to foster and support a culture of inquiry for novice to novice to mid-career investigators under the mentorship of experienced researchers. Priority areas for funding include the following:

This funding program is led by Dr. Sandra Carroll, Director, Clinical Health Professional Research, carroll@mcmaster.ca. Interested candidates are recommended to contact Dr. Carroll or Daniela Bianco biancdan@hhsc.ca in advance of their submission.

For more information and/or assistance, please contact Donna Catherwood, catherwood@hhsc.ca

Important Dates

Spring submission deadline: June 1
Fall submission deadline: October 31

Important Forms

HPI Application Form
HPI Budget Form
HPI Completion Report
HPI Guidelines for Application
HPI Progress Report

Submit to: HPI@hhsc.ca

Past Recipients 

2018 HPI Award Recipients

Clinical Health Professional Personnel Award (CHPA)

The Hamilton Health Sciences Clinical Health Professional Research Personnel Award is a one-time personnel stipend award. The award is to be used to help a suitably qualified non-physician health professional who has demonstrated an aptitude for research to pursue research in their discipline, by providing protected time through financial support for a portion of the applicant’s salary.

General Information

  • One new award will be offered in 2019 for the duration of one year. It is expected that the award will begin on July 1, 2019.
  • The value of the award will be up to $50,000 for the purpose of supporting up to 0.40 FTE protected time to be dedicated to research.
  • Funding may be extended for a second year, contingent upon the recipient’s demonstrated progress, productivity, and availability of funds. Refer to CHPA guidelines for requirements and process.

This funding program is led by Dr. Sandra Carroll, Director, Clinical Health Professional Research, carroll@mcmaster.ca. Interested candidates are recommended to contact Dr. Carroll or Daniela Bianco biancdan@hhsc.ca in advance of their submission.

For more information and/or assistance, please contact Donna Catherwood, catherwood@hhsc.ca

Important Dates

Submission deadline: May 1

Important Forms

CHPA Application Form
CHPA Guidlines for Application

Submit to: researchnetwork@hhsc.ca

Past Recipients 

2016 CHP Award Recipients

Clinical Health Professional Travel Awards (TA)

New Open Call Model to provide more flexibility to align with external conference deadlines, as well as clinical workload.

The Clinical Health Professionals Research Travel Award provides support for eligible non-physician Health Professionals to present their work at a scientific meeting of relevance to their practice/research. Up to six awards on a competitive basis will be given within a calendar year, and are each valued up to a maximum of $2,500 for a national conference or $3,500 for international (funds in Canadian dollars);

  • An abstract must be accepted for a national or international conference (not local or regional); and
  • applicants must be the first author on the abstract.

This funding program is led by Dr. Sandra Carroll, Director, Clinical Health Professional Research, carroll@mcmaster.ca. Interested candidates are recommended to contact Dr. Carroll or Daniela Bianco biancdan@hhsc.ca in advance of their submission.

For more information and/or assistance, please contact Donna Catherwood, catherwood@hhsc.ca

Open Call Model

Submission of Travel Awards application is required three months in advance of attending conference

Important Forms

TA Application Form
TA Expense Reimbursement Policy
TA Guidelines for Applications

Submit to: travelawards@hhsc.ca

Past Recipients 

2018 Travel Award Recipients 

Research Strategic Initiatives Request for Applications (RFA)

PLEASE NOTE: THERE WILL BE NO 2020 COMPETITION OFFERED

The Research Strategic Initiatives RFA Program is a competitive call to fund new research areas of high strategic priority to support emerging areas/teams with high potential for research success. This strategy will expand the existing base of research at Hamilton Health Sciences with the goal that a few new areas of research will achieve national or international stature within the next 5 to 10 years.

For more information contact Donna Catherwood, catherwood@hhsc.ca

Important Forms

RFA – Guidelines for Application
RFA Budget Template

Submit to: researchnetwork@hhsc.ca

Past Recipients 

2018 RFA Award Recipients