Neonatal Lupus Erythematosus

Neonatal lupus is a rare inflammatory condition that develops in unborn and newborn babies of women who carry anti-Ro, anti-La and/or anti-RNP antibodies. The most serious disease manifestation is congenital heart block, but infants may also develop rash, elevated liver enzymes, and low blood counts. The Neonatal Lupus Erythematosus (NLE) clinic was designed to assess infants at risk of developing NLE and to follow infants with any of the disease manifestations. Patients are typically seen at 6 weeks of life and then 2-3 more times in their first year.

For more information, visit the Rheumatology Clinic page for patients and families.

Patients/Conditions To Refer

Infants born to mothers with anti-Ro, anti-La and/or anti-RNP antibodies should be referred to the NLE clinic for assessment. Infants born to mothers who have autoimmune rheumatic diseases but do not carry anti-Ro, anti-La or anti-RNP antibodies do not need to be referred to NLE clinic. In addition, newborns with congenital heart block or other disease manifestations (i.e. neonatal lupus rash, elevated liver enzymes, low blood counts) thought to be secondary to NLE should be referred.


Referral & Contact Information


Phone: 905-521-2100 ext. 75382

Fax: 905-521-5056

NLE Referral Form

Assessment Options

  • In-person visits
  • Virtual consultations